How to elicit Nikolsky’s Sign in Pemphigus? (Video Demo)
October 27th, 2009
Watch out the video demonstration of how to elicit Nikolsky’s Sign in Dermatology, Nikolsky’s Sign is positive when slight rubbing of the skin results in exfoliation of the skin’s outermost layer, it is seen in Pemphigus, When autoantibodies attack desmogleins, the cells become separated from each other and the epidermis becomes “unglued”, a phenomenon called acantholysis.
Watch out the picture of a patient at Dr Ram Manohar Lohia Hospital showing Pemphigoid lesions over legs, the Nikolsky’s Sign is being shown in video below this picture.
pemphigus-on-legs
Watch out the video of Nikolsky’s Sign below
