Oral Submucous Fibrosis Treatment

by admin on May 9, 2010

Oral Submucous fibrosis is the commonly seen in India mostly in Muslim women who are in habit of eating Areca Nut (chhali).

Submucous fibrosis is characterised by inflammation, sometimes blisters form and ultimately fibrosis takes place, slowly and slowly fibrosis becomes more rigid and person is not able to open his mouth, when tries to open “trismus” occurs.

You can clearly see the blanching of the tissue in the photograph shown below.

Patient will come to you with complains of inability to open mouth, burning sensation in the mouth, intolerance to eating hot and spicy foods, sometimes mild hearing loss due to blockage of eustachian tube.

Oral submucous fibrosis is a precancerous condition leading to oral cancers.

Treatment: submucous is treated both by medical and surgical means

1. injection of dexamethasone mixed with hylase is given in oral cavity where fibrosis is seen so as to exclude side effects of oral steroids and is found to be more effective.

2. Vitamin supplements are given, and causative material like pan, supari, etc is advised to be avoided.

3. Jaw opening exercises are advised.

4. Spicy foods and consumption of chillies is avoided.

If not treated with medical means surgery is done, includes surgical removal of fibrotic bands, not very much successful as condition reoccurs.

Must also read submucous fibrosis article from WAENT.ORG

Watch out the excellent video showing submucous fibrosis and its treatment on youtube below.

For Further Reading :


{ 41 comments… read them below or add one }

Dr Puneet May 10, 2010 at 3:40 pm

now a days injection Kenacort is given which contain triamcinolone acetonide mixed with 2 % xylocaine is injected intralesionally starting from the retromolar trigone and then goes to the affected area


RUCHIKA March 11, 2011 at 10:31 am

Kenacort how much mg is given for smf in initial stages


admin March 11, 2011 at 5:41 pm

Ruchika we start with 40 mg kenacort.

milanshah April 23, 2011 at 12:35 am

sir .i have this problem scence20 years now that i do not eat pan masalafor last 4 years my doctor says your mouth will never open ,sir is there any treatment for me please help me


admin April 23, 2011 at 2:34 pm

Without seeing you we can not answer this question, so please visit your ENT doctor near you. Rest you can watch out the video of submucous fibrosis in the video. How many fingers can go inside your mouth by opening it wide?

anees May 11, 2011 at 1:48 pm

i have same problum 2 fingers only goes inside and beside the jaw looking like white .. i cant open my mouth plzz tell me some cure i have eaten ghuthka tobacco more in past


admin May 11, 2011 at 2:01 pm

cure is the same that we have shown in video.

Neeta Basu August 11, 2011 at 2:05 pm

Its scary.
I hv been diagnosed with submucous fibrosis very recently, and am taking Gris OD 375 (thrice a day) and Lycored (sofgel) twice/day. Besides mouth wash and mouth exercise. What else do u suggest?
Are u based in Delhi? If yes, may be I could meet up with u, and discuss my ailment.


admin August 11, 2011 at 9:22 pm

Yes we are from Delhi, you can meet us at Dr RML Hospital, what is your weight? you are taking extra doses of Gris OD ( we hope so) can say confirmly by knowing your weight, for submucous fibrosis, injection kenacort is given usually, you can visit us or any dental surgeon, call us at our helpline number.

Lilz September 16, 2011 at 3:01 pm

I have been chewing ghutka in the past but have left the habit since the last 6 years, I still havnt had much improvement in opening my mouth, I can barely put 3 fingers. What is the required dosage of the injection and for how many days?. I currently reside in Kenya and cannot travel out anytime soon, can you recommend anyone i kenya to be able to give me the injection? Or would it be possible for you to parcle it to me after i have sent you a draft for the respective charges?


admin September 16, 2011 at 4:44 pm

This problem will be solved only by taking treatment, you can visit any ENT specialist, We are providing details of few in your country
1. Dr Agugi John
Location: Afya Centre 8th Floor
Address: P.O.Box 59697 00200
Nairobi Kenya
2. Dr. Harish Rupani
Laboratory Block
Ardwings Kodhek Road
Tel no: + 254 20 272 7823
3. Dr Din Mujahuddin
Location: Doctors Plaza 4th Floor Room 429 3rd Parklands Avenue
Address: P.O.Box 41612 00100

If you still have any query feel free to ask

manish saxena September 16, 2011 at 4:55 pm

jst 4 month back doctor told me that i have Submucous fibrosis and he gave me royaceff and now monocef and it has been helpful bt still not fully cured.

pls advice


admin September 16, 2011 at 8:18 pm

what was the constituent in royaceff? monocef is an antibiotic, you must be given triamcinolone acetonide to be got treated.

manish June 4, 2013 at 1:03 pm

respected doctor,
its been 2 yr now since i have submucous fibrosis, got twice all blood test done, all normal, got biopsy done, all normal, got MRI and CT scan done and all normal.
i want to meet u and get treated asap.
please provide info where i can meet and get treated .

thanks n regards

arindam October 7, 2011 at 12:36 am

I am suffering from oral submucous fibrosis since last 6 months, Initially, I got burning sensation in the mouth. My mouth opening was 39 mm. I have consulted an ENT doctor, he suggested me Lyconeuron also, I have stopped any kind of tobacco intake, After, three months my burning sensation is almost healed, but mouth opening is still restricted. I feel stiffness in the mouth while opening.Also, I have one problem which is not healing is some kind of slight pinching pain for a second or more, which is radiating in my right ear, this is originating from inside and feels like slight problem in ear. According to the ENT doctor this is because of OSMF. But I am not getting any cure for this problem. Is there any complete cure for this problem. Since, As per the short knowledge, I got through internet,which indicates that it will definitely leads to oral cancer. Please, suggest me if any complete treatment is possible for this problem.

with regards,


admin October 7, 2011 at 8:15 am

Yes there is a solution available here, but we need to examine you to see your prognosis, if you can come to New Delhi, it will be better otherwise, you can visit your ENT consultant or Dental Surgeon.

rosina alam October 13, 2011 at 2:19 am

hello i have suffered from oral submucous fibrosis from the age of 11 and now i am 29 i have had 2 major operations this year unsucessful my mouth only opens 4 mm not even my tiny finger fits in my mouth i am doing exersise which is not helping at all please does anyone have any other advice the doctor said they cant do anything no more please email me on rosina_alam@hotmail.com or z3alam@hotmail.co.uk
thank you


admin October 13, 2011 at 5:11 am

We need to see you, examine you and then can comment, or can you provide the OT notes of those doctors who did your surgery.

rosina alam October 13, 2011 at 3:53 pm

ill try and get notes where is ur clinic is it in uk as i live in uk


admin October 13, 2011 at 8:00 pm

Well our clinic is in New Delhi, India.

Carla Ngirailemesang November 10, 2011 at 11:28 am

I’m from the Republic of Palau and I’ve been having problems with my mouth since I was 7 yrs old. I’m now 31 yrs old and on Oct. 17, 2011, I was diagnosed with Oral Submucous Fibrosis by the ENT Doctors at Triple Army Medical Center who visited our island. My mouth is unable to open wide and only one finger can get in there. I’m starting to have hearing problems. What I was told by the ENT doctor who saw me at the time was that there’s no cure for what I have. Please tell me what I can do or are there any medications that I can purchase? Since, we live in this small island we have limited resources and therefore, I humbly request a advise or mediations that can be purchased. Thank you and I will await for your response.


admin November 11, 2011 at 10:04 am

This can not be treated with medicines, some injection may be required, but even before that we need to examine you, if you can send some photographs of inside of your mouth, it can be of some help. Its better you consult some ENT surgeon near you.

sumant November 25, 2011 at 2:40 am

I am suffring from this problem since last 6 years and my family dentist has given me a kenacort gel for topical application with Antoxid once/day capsule. By the treatment with Kenacort injection the white fibrous layer will go or only we can open our mouth ???????


Hanumanth Reddy January 25, 2012 at 12:37 pm

I am suffering from oral submucos fibrosis. what will be the cost of surgical treatment.


admin January 25, 2012 at 1:05 pm

Free in Dr RML Hospital New Delhi

atish panda February 14, 2012 at 8:14 pm

sir i am detected ith osmf since 1 month, i am applying kenakort oral paste and have taken an injection of kena kort 40mg, i am taking lycopene vitamin tablets . i can open m mouth upto 50mm. but my burning sensation of mouth and throat is not decreased. please suggest any remedy…….


admin February 14, 2012 at 10:27 pm

Better to visit any ENT Surgeon near you, or visit ENT department at Dr Ram Manohar Lohia Hospital, New Delhi, if you want to meet any private surgeon linked to wacky5.com you need mail us at drvikram008@rediffmail.com but doctor will be available in New Delhi only, not in Orissa.

Vidya March 1, 2012 at 5:24 pm


My father has SSCHN (tongue cancer ) . He has undergone surgery as well as radio/chemo therapies. The cancer recurred and now he is unable to open his mouth at all and hence is unable to eat anything . Is there anything that can be done for his condition?


admin March 1, 2012 at 8:12 pm

squamous cell carcinoma of head and neck (SSCHN), ok, what is the status of his metastasis, has cancer metastasized? If not, something can be done, else nothing can be done except palliative care/cure.

Pawan March 2, 2012 at 11:37 am

I have been diagnosed for SMF on 14th of Feb recently (Only 15 days back). I was a tobacco chewer & smoker, but since then I left both completely. Now doctor said its only SMF (Grade-1) & has given Lycopene & Gummex.

My problem is that I am having rotating irritation in different parts of mouth. some times on lesft side some times on right side than upper parts then lower parts etc. Some times pain line goes to right ear also. I don’t have any problem of mouth opening, no irritation in spicy food. But very high Dry Mouth.

So I would like to visit your clinic for medical treatment. Please help if I can take some other precautionary medicine so that it doesn’t spread & get converted to Cancer. I am more worried on conversion of SMF to Oral Cancer. Please advice.


admin March 2, 2012 at 8:21 pm

Yes you can visit me you can send your complete details to us at drvikram008@rediffmail.com

Rosina alam March 19, 2013 at 12:13 am

Hello plz provide me with address were I can send my notes po please thanks


Dilip May 27, 2013 at 7:17 pm

I’ve been suffering from OSMF for more than 2 years. I haven’t got mouth-opening problem, but it has affected my voice. I can’t speak loudly or effectively. I quit tobacco for 2.5 years, but now I can’t even bear the smell of tobacco. if it happens, my voice gets affected. Multi-vitamin capsules helped in beginning, but now they do not, though I do get relief using Tantum oral rinse. Please advise permanent solution.



manish June 4, 2013 at 1:09 pm

respected doctor,its been 2 yr since i have submucous fibrosis, got twice all blood test done, got biopsy done, got MRI and CT scan done and all reports are normal.
please advice where i can meet u and treated asap.
please help.


manish June 4, 2013 at 7:14 pm



dr basit August 24, 2013 at 10:41 am

If any one suffering with OSMF and TMJ disorder in and around surat kindly contact me
I Am former resident AIIMS New Delhi Dental wing


Prabhat December 28, 2013 at 3:33 pm

I was trying to quit gutkha since april ’13, by reducing the quantity. Finally,I quit successfully quit in end of august’ 13. Consumtion of gutkha was very less between april to august (once in 2 to 3 days). I started LYCORED capsules without any doctor prescription which helped me to open my mouth but caused some kind of alergy in my mouth and in throat. I stopped LYCOred and consulted well recognized ENT specialist Surgeon of our area, he diagnosed OSMF, whiteness/blenching in mouth and some effect on Larynx also. He started my treatment with Stancool syrup(two teaspoon thrice a day), an antialergic tablet (hydroxyzine hydrochloride atarax 10 mg – one at night) and anti gasteric capsule (one in the morning). I am also taking Becasule/Zavit daily. Irritation against hot and spicey food, Whiteness on soft palate cheeks and gums is reducing, some area of inner cheeks are softer but bands are still visible in some areas. I am expereincing improvement. I can open my mouth more than 35mm now, which was lessthan 28 mm earlier.

I tried to take lycopene from other sources (carrot,tomatoe and beetroot salad), but i felt again acidity and some itching(or allergy) in my mouth.

I am under treatment from last three months. I just want to confirm that the above treatment is sufficient(and standard) and all will be OK after some time ? How long will it take to cure completely ?



Appu March 27, 2014 at 9:39 pm

Sir ,

Hello actually iam suffering from the same problem Oral SMF i Have taken Injections in my mouth by ENT surgeon at kamineeni i have taken only 4 doses of Solumedrol, and phlogam Tab & Acicrol syrup ,and Ato Z capsules and stopped past 6 years back in this meantime i have stopped all the pan masala everything , but recently it has started again i am stopping it can you please suggest is anyone of your Collegues ENT Surgeon reside in hyderabad Sir I will be waiting for your reply Sir
Thyanking You


B.Sanghvi May 13, 2014 at 3:27 pm

am suffering from this problem since last 6 years , Do you have any doctor contact details in Gujarat-Surat


anonymous August 8, 2014 at 3:06 pm

The problem is ..why we hook on chewing or smoking
Its psychological.addictive. chemicals.
Self support is absent when we r gtng hooked to such things
Injection n antioxidants r available as well as doctors
Address n mail
Thank god
Read above. Aloe vera is slow n natural remedy
N dont chew pan paragraph.sweety supari.pan bahar
Rajnigandha pan masala, evn shikhar, dilbag,
Silver coated elaichi helps to get rid of psychological tobacco chewing habit
Iam a female.
Hope things start to get better n everyone recieves a ray of hope


ravi srivastava July 5, 2016 at 6:00 pm

dear sir,

my name is ravi srivastava,i am from lko, i am suffering from osmf ,my mouth opening is 5 mm .please suggest the need full.


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